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| EDUCATION Medical Undergraduate:
Genetics is taught in the following sections of the integrated medical curriculum of the faculty:
Introductory Basic Sciences Stream: Ten lectures in basic medical genetics.
Applied Sciences Stream: Reproductive Health Module - Six lectures in clinical genetics.
Behavioural Sciences Stream: A lecture on "Moral and Ethical Issues in Genetics".
Community Stream: A lecture on the effects of genetics on Family and Community. Forensic Medicine - Role of DNA in Forensic Medicine
Medical Postgraduate:
Pre-MD/MS Part I courses are conducted for students who plan to follow the following courses:
MS - Surgery
MD - Obstetrics & Gynaecology
MD - General Medicine MD - Paediatrics
MD - Psychiatry Genetic courses are conducted as part of the following postgraduate courses offered by the University: MD - Obstetrics and Gynaecology (Subspecialisation in Infertility) [Clinical attachment in Genetics]
MD - Medicine [Elective in Genetics] MD - Transfusion Medicine [Clinical Attachment in Genetics]
MD - Oncology & Radiotherapy
MSc - Medical Administration
MD - Forensic Medicine Diploma in Legal Medicine and Forensic Science
MS - Dental Surgery
MSc - Community Medicine / Dentistry
MD - Ophthalmology MD Medical Adiminstration Diploma - Family Medicine Diploma - Reproductive Health Certificate in Basic Laboratory Sciences
MSc Biomedical Informatics BSc Physiotherapy Undergraduates:
Basic Sciences Stream: Eight lectures in basic medical genetics.
Clinical Stream: Six lectures in clinical genetics.
Allied Health Sciences Professionals: Certificate course in Genetics for Nurse Postgraduate Research Students [MPhil/PhD]: The current PhD students:
Dr. Nilakshi Samaranayake (Probationary Lecture, Department of Parasitology, University of Colombo); Project title: A candidate gene association study of cutaneous leishmaniasis in Sri Lanka.
Dr. K. T. Wettasinghe (Research Assistant, Human Genetics Unit, Faculty of Medicine, University of Colombo); Project title: The role of Y-chromosome microdeletions in male factor sub fertility and recurrent pregnancy loss. Ms. G. Harendra (Probationary Lecturer, Department of Zoology, University of Colombo); Project title: Inherited factors in pre-eclampsia and weight of babies at birth: investigations on the role of the heparin binding epidermal factor (HB-EGF) gene. Dr. T. Chenthuran (Probationary Lecturer, Department of Anatomy, University of Jaffna); Project title: Inherited factors in pre-eclampsia: investigations on the role of the Epidermal Growth Factor gene. Ms. Ranamalee Amarasekara; Project title: A comparative study of viruses, bacteria and fungi present in blood, urine, amniotic fluid, and placental tissue of women with pre-eclampsia and normal pregnant women using molecular genetic techniques. Ms. A. Kuruppu; Project title: Investigations on the role of polymorphisms in the epidermal growth factor gene in the aetiology of breast cancer in a Sri Lankan population Objectives
• To genotype 328 women with breast cancer (cases) and 328 women who have never been diagnosed to have any malignancy (controls) for the polymorphisms- rs4444903G>A, rs11568835G>A and rs3756261A>G in the EGF gene.
• To compare allele frequencies of rs4444903G>A, rs11568835G>A and rs3756261A>G polymorphisms in cases and controls to determine whether these polymorphisms are associated with the susceptibility to breast cancer.
• To compare haplotype frequencies of the haplotypes defined by the rs4444903G>A, rs11568835G>A and rs3756261A>G polymorphisms of the EGF gene in breast cancer cases and controls to determine whether any haplotype is associated with the susceptibility to breast cancer.
• To carry out a sub group analysis to determine whether the genotypes and haplotypes affect factors such as the age of onset of breast cancer, stage of disease at diagnosis, the number and distribution of lymph nodes affected at diagnosis and recurrence of the condition at 6 months, 12 months, 18 months and 24 months. This project is awaiting ethics and research approval. | |
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