Publications

2015

  1. [IF 1.669] Kalpage HA, Sumathipala DS, Goonasekara HW, Dissanayake VHW.Study on Hereditary Thrombophilia and Stroke in a Cohort from Sri Lanka. Journal of Stroke and Cerebrovascular Diseases. 2015 Oct 27. [Epub ahead of print]. DOI: http://dx.doi.org/10.1016/j.jstrokecerebrovasdis.2015.08.042
  1. Sumathipala DS, Mandawala EM, Sumanasena SP, Dissanayake VHW.17p11.2 and Xq28 duplication detected in a girl diagnosed with Potocki–Lupski syndrome. BMC Res Notes (2015) 8:506. DOI 10.1186/s13104-015-1439-7
  1. [IF 3.481] Chan SL, Samaranayake N, Ross CJD, Toh MT, Carleton B, Hayden MR, Teo YY, Dissanayake VHW, Brunham LR. Genetic Diversity of Pharmacogenomic Variants in Sri Lanka: implications for clinical implementation. Pharmacogenetics and Genomics. 2015 Oct 6. [Epub ahead of print]. DOI: 10.1097/FPC.0000000000000182.
  1. [IF 2.083 ] Sirisena ND, Hidellage N, Kariyawasam KJC, Jayasekara RW, Dissanayake VHW. Novel AGXT gene mutation in a Sri Lankan family with Primary Hyperoxaluria type 1. Nephrology. [Accepted on 20 July 2015]
  1. [IF 15.84] Manolio TA, Abramowicz M, Al-Mulla F, Anderson W, Balling R, Berger AC, Bleyl S, Chakravarti A, Chantratita W, Chisholm RL, Dissanayake VHW, Dunn M, Dzau VJ, Han BG, Hubbard T, Kolbe A, Korf B, Kubo M, Lasko P, Leego E, Mahasirimongkol S, Majumdar PP, Matthijs G, McLeod HL, Metspalu A, Meulien P, Miyano S, Naparstek Y, O’Rourke PP, Patrinos GP, Rehm HL, Relling MV, Rennert G, Rodriguez LL, Roden DM, Shuldiner AR, Sinha S, Tan P, Ulfendahl M, Ward R, Williams MS, L Wong JE, Green ED, Ginsburg GS. Global implementation of genomic medicine: We are not alone. Science Translational Medicine 2015;7(290):290ps13. doi: 10.1126/scitranslmed.aab0194.
  1. Ranasinghe JC, Chandradasa D, Fernando S, Kodithuwakku U, Mandawala DEN, Dissanayake VHW. Angelman syndrome presented with a rare seizure type in a patient with 15q11.2 deletion: a case report. Journal of Medical Case Reports 2015; 9:142. DOI 10.1186/s13256-015-0622-8
  1. Gooneratne LV, Dissanayake R, Jayawardena A, Jayaweera G, Abayadeera A, Samarasinghe M, Chandrasir P, Dissanayake VHW, Weerasinghe T, Brambilla CZ, Manna N, Faulkner LB. Allogeneic bone marrow transplant in a child with thalassaemia. Ceylon Medical Journal 2015; 60: 74-5. DOI: 10.4038/cmj.v60i2.8159
  1. [IF 2.083] Sirisena ND, Thalgahagoda S, Abeyagunawardena A, Neumann M, Schmudlach , Jayasekara RW, Dissanayake VHW. Novel COL4A3 Gene Mutations in a Consanguineous Family with Autosomal Recessive Alport Syndrome. Nephrology (Carlton) 2015; 20(8):580. DOI: 10.1111/nep.12430.
  1. [IF 1.208] Andraweera PH, Dekker GA, Jayasekara RW, Dissanayake VHW, Roberts CT, Polymorphisms in the inflammatory pathway genes and the risk of preeclampsia in Sinhalese women, Journal of Maternal Fetal and Neonatal Medicine, Early Online: 1–5, 2015. DOI: 10.3109/14767058.2015.1034102
  1. Somadasa PKDCT, Sirisena ND, De Silva LSC, Dissanayake, VHW. A Sri Lankan family with cerebellar hemangioblastoma due to a heterozygous nonsense mutation in the von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (VHL) gene. Sri Lanka Journal of Surgery 2014; 33(1): 30-32
  1. [IF 2.005] Andraweera PH, Dekker GA, Jayasekara RW, Dissanayake VHW, Roberts CT. The obesity related FTO gene variant associates with the risk of recurrent miscarriage. Acta Obstetricia et Gynecologica Scandinavica. Epub 2015 Apr 2. DOI: 10.1111/aogs.12640.

2014

1.    Somadasa PKDCT, Sirisena ND, De Silva LSC, Dissanayake, VHW. A Sri Lankan family with cerebellar hemangioblastoma due to a heterozygous nonsense mutation in the von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase (VHL) gene. Sri Lanka Journal of Surgery 2014; 33(1): 30-32

2.    Andraweera PH, Dekker GA, Jayasekara RW, Dissanayake VHW, Roberts CT. The obesity related FTO gene variant associates with the risk of recurrent miscarriage. Acta Obstetricia et Gynecologica Scandinavica. Epub 2015 Apr 2. DOI: 10.1111/aogs.12640.

3.    de Abrew A, Dissanayake VHW, Korf BR. Challenges in global genomics education. Applied and Translational Genomics 2014; 3(4): 128-129.
DOI: http://dx.doi.org/10.1016/j.atg.2014.09.015

4.    Sirisena ND, Dissanayake VHW. Cancer Genetics and the Surgeon – New Frontiers. Sri Lanka Journal of Surgery 2014; 32(2): 12-19.
DOI: http://dx.doi.org/10.4038/sljs.v32i2.7350

5.    Amarasekara R, Jayasekara RW, Senanayake H, Dissanayake VHW. The microbiome of the placenta in preeclampsia supports the role of bacteria in the multifactorial aetiology of pre-eclampsia. Journal of Obstetrics and Gynaecology Research. 2014 Dec 10. DOI: http://dx.doi.org/10.1111/jog.12619 [Epub ahead of print]

6.    Gunathilake KMD, Sirisena UND, Nisansala PKD, Goonasekera HWW, Jayasekara RW, Dissanayake VHW. The prevalence of the Prothrombin (F2) 20210G>A mutation in a cohort of Sri Lankan patients with thromboembolic disorders. Indian Journal of Haematology and Blood Transfusion. 2014 Sep 2. DOI: 10.1007/s12288-014-0452-7

7.    Andraweera PH, Dekker GA, Thompson SD, Nowak RC, Jayasekara RW, Dissanayake VHW, Roberts CT. Polymorphisms in the fibrinolytic pathway genes and the risk of recurrent miscarriage. Reproductive Biomedicine Online. 2014 Dec;29(6):745-51. DOI: 10.1016/j.rbmo.2014.08.014. Epub 2014 Sep 16.

8.    Sirisena N, McElreavey K, Bashamboo A, de Silva K, Jayasekara R, Dissanayake VHW.
A child with a novel de novo mutation in the aristaless domain of the aristaless-related homeobox (ARX) gene presenting with ambiguous genitalia. Sexual Development 2014;8(4):156-9. DOI: 10.1159/000365458. Epub 2014 Jul 25.

9.    Dissanayake VHW, Sumathipala WLDS, Kariyawasam UGAC, JMDNMM Jayamanne,
Nisansala PKDS, Lie R.  A Survey of Scientist and Policy Makers’ Attitudes Towards Research On Stored Human Biological Materials In Sri Lanka. Developing  World Bioethics. 2014 Oct 3. DOI: http://dx.doi.org/10.1111/dewb.12065.

10.    Andraweera PH, Dissanayake VHW,  Jayasekara RJ, Dekker GA, Roberts CT. Hypoxia-inducible factor-1a gene polymorphisms in early and late onset preeclampsia in Sinhalese women. Placenta 2014;35(7):491-5. DOI: 10.1016/j.placenta.2014.04.008. Epub 2014 May 2.

11.    Thillainathan S, Sirisena ND, Kariyawasam KWJC, Jayasekara RW, Dissanayake VHW. Cytogenetic analysis of chromosomal abnormalities in Sri Lankan children. World Journal of Pediatrics. 2014 Nov 20. DOI: DOI: 10.1007/s12519-014-0526-5

12.    Chenthuran T, Harendra GG, Jayasekara RW, Dissanayake VHW. Polymorphism in the Epidermal Growth Factor (EGF) gene is associated with pre-eclampsia and low birth weight. Journal of Obstetrics and Gynaecology Research.  2014 May;40(5):1235-42. DOI: 10.1111/jog.12362.

2013

  1. Sumathipala DS, Jayasekara RW, Dissanyake VHW. The initial study of clinical and molecular genetic features of Huntington’s disease in Sri Lanka. BMC Neurology. BMC Neurology 2013, 13:191 doi:10.1186/1471-2377-13-191.
  2. Chenthuran T, Harendra GG, Jayasekara RW, Dissanayake VHW. Polymorphism in the Epidermal Growth Factor (EGF) gene is associated with pre-eclampsia and low birth weight. Journal of Obstetrics and Gynaecology. In Press.
  3. Tharanga TDP, Jinadasa CMV, Risama MF, Galappatthy P, Jayakody RL, Dissanayake VHW. Genetic variants in the Cytochrome P4502D6 (CYP2D6) gene in the Sri Lankan population. Indian Journal of Human Genetics. In Press.
  4. Pedurupillay CRJ, Misceo D, Gamage TH, Dissanayeke VHW, Frengen E. Post-zygotic breakage of a dicentric chromosome results in mosaicism for a telocentric 9p marker chromosome in a boy with developmental delay. Gene. 2014 Jan 1;533(1):403-10. doi: 10.1016/j.gene.2013.09.090. Epub 2013 Oct 2.
  5. Dissanayake R, De Silva KSH, Lekamwasam S, Abeysekara AAGS, Dissanayake VHW. Thalassaemic Osteopathy:-a cross-sectional preliminary study from Sri Lanka. Journal of Pediatric Endocrinology and Metabolism. J Pediatr Endocrinol Metab. 2013 Oct 16:1-4.doi: 10.1515/jpem-2013-0104.
  6. Kulatunga GGAK, Marasinghe RB, Karunathilake IM, Dissanayake VHW. Development and implementation of a web-based continuing professional development (CPD) programme on medical genetics. Journal of Telemedicine and Telecare. 2013 19: 388-392, DOI:10.1177/1357633X13506525
  7. Sirisena N, Wijetunge UKS, de Silva R, Dissanayake VHW. Child with Deletion 9p Syndrome Presenting with Cranio-facial Dysmorphism, Developmental Delay and Multiple Congenital Malformations. Case Reports in Genetics 2013;2013:785830. DOI: 10.1155/2013/785830
  8. Sumathipala DS, Abeysekara AAGS, Jayasekara RW, Tallaksen CME, Dissanayake VHW. Autosomal dominant hereditary ataxia in Sri Lanka. BMC Neurology 2013, 13:39. DOI:10.1186/1471-2377-13-39.
  9. Andraweera PH, Dekker GA, Dissanayake VHW, Bianco-Miotto T, Jayasekara RW, Roberts CT. Vascular endothelial growth factor family gene polymorphisms in preeclampsia in Sinhalese women in Sri Lanka. The Journal of Maternal-Fetal and Neonatal Medicine 2013;26(5):532-6. DOI: 10.3109/14767058.2012.743520. Epub 2012 Nov 21.

2012

  1. Wettasinghe TK, Jayasekara RW, Dissanayake VHW. The low frequency of Y chromosome microdeletions in subfertile males in the Sinhalese population of Sri Lanka. Indian Journal of Human Genetics 2012;18(3):320-325.
  2. Padeniya PM, Godapitiya I, Pathirana Dr, Jayasekara RW, Dissanayake VHW. A Sri Lankan Child with 48,XXXX syndrome. Indian Journal of Paediatrics. doi: 10.1007/s12098-013-0995-x
  3. Samarakoon L, Sirisena ND, Wettasinghe KT, Kariyawasam KWJC, Jayasekara RW, Dissanayake VHW. Prevalence of chromosomal abnormalities in Sri Lankan women with primary amenorrhea.Journal of Obstetrics and Gynaecology Research 2013;39(5):991